abstract：:The aim of our study was to examine NPHS1, NPHS2, WT1 and LAMB2 mutations, previously reported in two thirds of patients with nephrotic syndrome with onset before the age of one year old. Genomic DNA samples from Polish children (n=33) with Steroid-Resistant Nephrotic Syndrome (SRNS) due to focal segmental glomerulosc...

journal_title：Bosnian journal of basic medical sciences

authors： Bińczak-Kuleta A,Rubik J,Litwin M,Ryder M,Lewandowska K,Taryma-Leśniak O,Clark JS,Grenda R,Ciechanowicz A

更新日期：2014-05-01 00:00:00

abstract：:The objective of our work was to investigate the influence of Fasudil, a Rho inhibitor on the number and function of the late endothelial progenitor cells in peripheral blood of chronic obstructive pulmonary diseases (COPD) patients with pulmonary artery hypertension. Eighty COPD patients with pulmonary artery hyperte...

journal_title：Bosnian journal of basic medical sciences

authors： Liu P,Zhang H,Tang Y,Sheng C,Liu J,Zeng Y

更新日期：2014-02-01 00:00:00

abstract：:Epilepsy is one of the most common neurological disorders, characterized by recurrent seizures, which may increase the content of reactive oxygen and nitrogen species. The objective of this study was to investigate the effects of Neuropeptide Y on oxidative and nitrosative balance and brain-derived neurotrophic factor...

journal_title：Bosnian journal of basic medical sciences

authors： Kir HM,Sahin D,Oztaş B,Musul M,Kuskay S

更新日期：2013-11-01 00:00:00

abstract：:The aim of study was to evaluate endocrine changes in PCOS women during metformin treatment. One hundred women with PCOS, aged 20-40 years were included. A complete hormonal and metabolic pattern was recorded for each subject every 6 months. Metformin treatment after 6 and 12 months significantly reduced weight, BMI, ...

journal_title：Bosnian journal of basic medical sciences

authors： Velija-Ašimi Z

更新日期：2013-08-01 00:00:00

abstract：:The nonparasitic primary splenic cysts are very rare clinical entity. In the past, splenectomy was the treatment of choice but with the recognition of the spleen's important immunological function, spleen-preserving surgery is the preferred treatment modality. We hereby present a case of a large splenic mesothelial cy...

journal_title：Bosnian journal of basic medical sciences

authors： Zvizdić Z,Karavdić K

更新日期：2013-05-01 00:00:00

abstract：:The new criteria in detection of ARVC/D produced more subtle noninvasive parameters that raised sensitivity in diagnosis. Since heart rate dynamics have prognostic significance for the progression of a disease and for mortality, the main objective was to explore its value in disclosing risk for serious arrhythmias. Ou...

journal_title：Bosnian journal of basic medical sciences

authors： Vranic I

更新日期：2013-02-01 00:00:00

abstract：:Large scale genetic association meta-analyses showed that neurocan (NCAN) gene polymorphism rs1064395 is susceptibility locus for bipolar disorder. These studies also included patients with bipolar disorder originated from Bosnia and Herzegovina. Followed by theory of shared genetic elements between bipolar disorder a...

journal_title：Bosnian journal of basic medical sciences

authors： Oruč L,Kapur-Pojskić L,Ramić J,Pojskić N,Bajrović K

更新日期：2012-11-01 00:00:00

abstract：:The objective of our study was to evaluate bladder outlet obstruction number (BOON) in order to predict infravesical obstruction in patients with benign prostatic enlargement (BPE). Two hundred patients with proven BPE from daily urological practice at the Urology Department of the Sarajevo University Clinical Centre ...

journal_title：Bosnian journal of basic medical sciences

authors： Aganovic D,Spahovic H,Prcic A,Hadziosmanovic O

更新日期：2012-08-01 00:00:00

abstract：:Trefoil Factor Family (TFF) plays an essential role in the intestinal epithelial restitution, but the relationship between TFF1 and gastric cancer (GC) is still unclear. The present study aimed to determine the role of TFF1 in repairing gastric mucosa and in the pathogenesis of GC. The TFF1 expression in different ga...

journal_title：Bosnian journal of basic medical sciences

authors： Ge Y,Zhang J,Cao J,Wu Q,Sun L,Guo L,Wang Z

更新日期：2012-05-01 00:00:00

abstract：:The current study evaluates the impact of high saturated fat feeding in rat model of experimental nephrotoxicity induced by gentamicin. Sprague-Dawley rats weighing 200 g were randomized into four groups; the first one received the standard rodents chow for 8 weeks and was treated as control, the second group (HFD)rec...

journal_title：Bosnian journal of basic medical sciences

authors： Ibraheem ZO,Sattar MA,Abdullah NA,Rathore HA,Johns EJ

更新日期：2012-02-01 00:00:00

abstract：:Owing to its unique nutritional and immunological characteristics, breast milk is the most important food source for infants. But, children are at greater risk for exposure to environmental toxicants from breast milk. The aim of this study was to evaluate the influence of environmental pollution on essential and toxic...

journal_title：Bosnian journal of basic medical sciences

authors： Cinar N,Ozdemir S,Yucel O,Ucar F

更新日期：2011-11-01 00:00:00

abstract：:Most of today available non-invasive procedures cannot clearly determinate between benign and malignant solitary pulmonary nodules (SPN). The purpose of the study was to assess the possibility of using 99mTc labeled hexakis-2-methoxyisobutylisonitrile (99mTc-MIBI) to differentiate benign from malignant SPN. Sixty pati...

journal_title：Bosnian journal of basic medical sciences

authors： Nikoletic K,Lucic S,Peter A,Kolarov V,Zeravica R,Srbovan D

更新日期：2011-08-01 00:00:00

abstract：:Kidney transplantation (Ktx) is generally performed during end stage renal disease due to a loss of the kidneys' ability to filter wastes from the circulatory system. Acute graft-versus-host disease (GVHD) after Ktx is a life-threatening complication that progresses to organ failure, systemic complications, and death....

journal_title：Bosnian journal of basic medical sciences

authors： Pintar T,Alessiani M,Pleskovič A,Pleskovič A,Zorc-Pleskovič R,Milutinović A

更新日期：2011-05-01 00:00:00

abstract：:The objective of this study was to investigate the ability of biofilm formation among mutans and non mutans oral streptococci and to determine the effect of Lactobacillus acidophilus DSM 20079 as a probiotic strain on the adhesion of selected streptococcal strains on the surfaces. The sample comprised 40 isolates of o...

journal_title：Bosnian journal of basic medical sciences

authors： Tahmourespour A,Kermanshahi RK

更新日期：2011-02-01 00:00:00

abstract：:This is the first study performed in population from Bosnia & Herzegovina (BH), in which we analysed a significance of genetic variations in drug-metabolising enzyme, cytochrome P450 (CYP), in pathogenesis of Type 2 diabetes. We have determined allele frequencies for CYP2C9*2, CYP2C19*2, and CYP2D6*4 in diabetic patie...

journal_title：Bosnian journal of basic medical sciences

authors： Semiz S,Dujic T,Ostanek B,Prnjavorac B,Bego T,Malenica M,Marc J,Causevic A

更新日期：2010-11-01 00:00:00

abstract：:Potential risk of sudden death during sports participation makes screening of competitive athletes of vital importance. Congenital cardiac anomalies and non-atherosclerotic, acquired myocardial conditions are primary causes underlying exercise-induced cardiac death in young patients. Since cardiovascular conditions ar...

journal_title：Bosnian journal of basic medical sciences

authors： Mesihović-Dinarević S,Kulić M,Kreso A

更新日期：2010-08-01 00:00:00

abstract：:The aim of this study was to assess echocardiographic changes in female patients with untreated dysfunctional thyroid states and whether the therapy aimed to normalize the thyroid dysfunction could lead to improvement in cardiac systolic and diastolic function. The study included 90 female subjects who performed contr...

journal_title：Bosnian journal of basic medical sciences

authors： Hadzović-Dzuvo A,Kucukalić-Selimović E,Nakas-Ićindić E,Rasić S,Begić A,Al Tawil D,Valjevac A,Avdagić N,Lepara O

更新日期：2010-05-01 00:00:00

abstract：:The research has included 422 patients aged between 25 to 60, of whom 341 were men and 81 women. The purpose of research was to determine impact of diet and physical activity in the treatment of metabolic syndrome during the six month period. Processing of results through descriptive and discriminative analysis have i...

journal_title：Bosnian journal of basic medical sciences

authors： Dragusha G,Elezi A,Dragusha S,Gorani D,Begolli L

更新日期：2010-05-01 00:00:00

abstract：:The aim of this study was to analyze the importance of the peritoneal equilibration test (PET) in evaluation of the peritoneal membrane transport status in patients treated with continuous ambulatory peritoneal dialysis (CAPD). The study included 30 adult continuous ambulatory peritoneal dialysis (CAPD) patients, 16 m...

journal_title：Bosnian journal of basic medical sciences

authors： Uncanin S,Rasić S,Rebić D,Dzemidzić J,Muslimović A,Begović B,Herenda V

更新日期：2010-04-01 00:00:00

abstract：:Methylenetetrahydrofolate Reductase (MTHFR) is key enzyme in metabolism of homocysteine. Homozygotes for mutation (TT genotype) have hyperhomocysteinemia, risk factor for atherosclerosis development. The aim of the study was to find out distribution of genotype frequencies of C677T MTHFR among patients on maintenance ...

journal_title：Bosnian journal of basic medical sciences

authors： Kiseljaković E,Resić H,Kapur L,Hasić S,Jadrić R

更新日期：2010-04-01 00:00:00

abstract：:Physical capacity of athletes is an important element of success in sports achievements. Aerobic capacity has been accepted as its major component. Maximal oxygen uptake (VO2max) has been regarded by majority of authors as the best indicator of aerobic capacity of an organism, and at the same time, the best indicator ...

journal_title：Bosnian journal of basic medical sciences

authors： Rankovic G,Mutavdzic V,Toskic D,Preljevic A,Kocic M,Nedin Rankovic G,Damjanovic N

更新日期：2010-02-01 00:00:00

abstract：:Number of hemodialysis patients each day is increasing. The quality of their lives is largely determined by the quality of hemodialysis treatment. One of the most important factors is the type of applied blood approach. The type of blood approach in the most case is artery venous fistula, permanent, temporary catheter...

journal_title：Bosnian journal of basic medical sciences

authors： Kukavica N,Resic H,Sahovic V

更新日期：2009-11-01 00:00:00

abstract：:One of the most frequent hereditary causes of thrombophilia is, without a doubt, resistance to Activated Protein C (APC-resistance), which is a consequence of point mutation in gene coding for coagulation Factor V (Factor V Leiden) in 90-95% of cases. The aim of this paper was to determine prevalence of APC-resistance...

journal_title：Bosnian journal of basic medical sciences

authors： Mekaj Y,Zhubi B,Hoxha H,Belegu R,Mekaj A,Miftari E,Belegu M

更新日期：2009-11-01 00:00:00

abstract：:In parallel to technological advances in late twentieth century, medical diagnostics and therapeutic options greatly improved. A surge of evidence-based research in intensive care medicine provided additional opportunities and the "best" medical practice has been changing rapidly. However, the primary focus of Hippocr...

journal_title：Bosnian journal of basic medical sciences

authors： Festic E,Gajic O

更新日期：2009-10-01 00:00:00

abstract：:Atherosclerosis is a pathological condition that begins in early childhood, but clinically the disease manifests in older age. The aim of work was to determine frequency of atherosclerosis risk factors in healthy school children. Cross-sectional study included 214 children in mean age 10,99+/-2,52 years, within range ...

journal_title：Bosnian journal of basic medical sciences

authors： Sporisević L,Krzelj V,Bajraktarević A,Jahić E

更新日期：2009-08-01 00:00:00

abstract：:Preeclampsia is referred to as the "disease of the theories" because of the multiple hypotheses proposed to explain is occurrence. Despite considerable research, the causes of preeclampsia remain unclear. Preeclampsia is likely to be multifactorial in origin, and recent research has focused on endothelial dysfunction ...

journal_title：Bosnian journal of basic medical sciences

authors： Stefanović M,Vukomanović P,Milosavljević M,Kutlesić R,Popović J,Tubić-Pavlović A

更新日期：2009-08-01 00:00:00

abstract：:The synergy and shared co-morbidity, certainly interplay between kidney and cardiovascular disease, where advanced renal failure influences on progression of cardiac disease in bi-direction relationship. Cardiovascular diseases are cause of death in almost 50% of uremic patients. Correction of uremia after successful ...

journal_title：Bosnian journal of basic medical sciences

authors： Dzemidzić J,Rasić S,Saracević A

更新日期：2009-05-01 00:00:00

abstract：:The evolution of homocysteine (Hcy) changes after acute myocardial infarction is still not elucidated. Serum Hcy concentration has been shown to increase between acute and convalescent period after myocardial infarction and stroke. Also a decrease in serum Hcy during acute phase was observed. It is still not clear whe...

journal_title：Bosnian journal of basic medical sciences

authors： Valjevac A,Dzubur A,Nakas-Ićindić E,Hadzović-Dzuvo A,Zaćiragić A,Lepara O,Arslanagić A

更新日期：2009-05-01 00:00:00

abstract：:After lung cancer colorectal cancer (Cc) is ranked the second, as a cause of cancer-related death. The purpose of this study was to analyze the Cc cases in our material with respect to all prognostic values including histological type and grade, vascular invasion, perineural invasion, and tumor border features. There ...

journal_title：Bosnian journal of basic medical sciences

authors： Manxhuka-Kerliu S,Telaku S,Ahmetaj H,Baruti A,Loxha S,Kerliu A

更新日期：2009-02-01 00:00:00

abstract：:Primary skin melanoma and skin cancers have been more prevalent in the previous decades and therefore have become a very significant public health problem. Dermatologists of the Skin and Venereal Diseases Clinic of the University of Sarajevo Clinics Centre initiated the first public preventive action called "Days of F...

journal_title：Bosnian journal of basic medical sciences

authors： Alendar F,Drljević I,Drljević K,Alendar T

更新日期：2009-02-01 00:00:00

abstract：:Obese patients with type 2 diabetes and impaired glucose tolerance are at increased risk of development of cardiovascular diseases. Endothelial dysfunction may be a reason for development of atherosclerosis and cardiovascular diseases. Lifestyle modification, increased physical activity, weight reduction, energy restr...

journal_title：Bosnian journal of basic medical sciences

authors： Ascić-Buturović B,Kacila M

更新日期：2008-11-01 00:00:00

abstract：:There is still debate whether sintethic graft (polytetrafluoroethylene or Dacron) is equivalent to vein as bypass graft material for the above-knee femoropopliteal bypass. Therefore, we performed prospective randomized trial to compare vein with polytetrafluoroethylene/dacron for femoropopliteal bypasses with the dist...

journal_title：Bosnian journal of basic medical sciences

authors： Solaković E,Totić D,Solaković S

更新日期：2008-11-01 00:00:00

abstract：:Numerous studies conducted on acetylsalicylic acid (ASA, aspirin) confirmed that ASA inhibits proliferation and induces apoptosis in various types of human cells. Therefore, it was of interest to examine possible effects of different concentrations of ASA on viability and proliferation of lymphocytes in the cell cultu...

journal_title：Bosnian journal of basic medical sciences

authors： Dujić T,Causević A,Malenica M

更新日期：2008-08-01 00:00:00

abstract：:Staphylococcus aureus has long been recognized as one of the leading cause of hospital infections all over the world. Increased frequency of methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized patients and possibility of vancomycin resistance requires rapid and reliable characterization of isolates and ...

journal_title：Bosnian journal of basic medical sciences

authors： Ostojić M

更新日期：2008-08-01 00:00:00

abstract：:Intracerebral hemorrhage is the deadliest, most disabling and least treatable form of stroke despite progression in medical science. The aim of the study was to analyze the frequency, risk factors, localization and 30-day prognosis in patients with intracerebral hemorrhage. We analyzed 352 patients with intracerebral ...

journal_title：Bosnian journal of basic medical sciences

authors： Smajlović D,Salihović D,C Ibrahimagić O,Sinanović O,Vidović M

更新日期：2008-05-01 00:00:00

abstract：:Aminoglycoside antibiotics are obligated nephrotoxins and inevitably cause renal failure during prolonged use. Experimental models of gentamicin-induced nephrotoxicity have shown histopathological, ultrastructural and functional alteration with blood urea nitrogen and serum creatinine increase leading to acute renal i...

journal_title：Bosnian journal of basic medical sciences

authors： Stojiljković N,Veljković S,Mihailović D,Stoiljković M,Radovanović D,Randelović P

更新日期：2008-05-01 00:00:00

abstract：:Aim of this study was to evaluate the biotransformation of simple phenols after ingestion of edible fruits and mixed food. It was analyzed hippuric acid in urine as biomarker of conjugation in the liver cells of glycine with aromatic phenolic acids such benzoic and salicylic acid from ingested food. Measurement of hip...

journal_title：Bosnian journal of basic medical sciences

authors： Toromanović J,Kovac-Besović E,Sapcanin A,Tahirović I,Rimpapa Z,Kroyer G,Sofić E

更新日期：2008-02-01 00:00:00

abstract：:Stability testing of an active substance or finished product provides information of the variation of drug substance or final product with time influenced by a variety of environmental factors such as temperature, humidity and light. Knowledge gained from stability studies enables understanding of the effects of the e...

journal_title：Bosnian journal of basic medical sciences

authors： Uzunović A,Vranić E

更新日期：2008-02-01 00:00:00

abstract：:We investigated serum concentration of C-reactive protein (CRP) and measures of adiposity in 30 patients with type 2 diabetes mellitus (15 male, 15 female) and 30 age and sex-matched apparently healthy subjects. CRP concentration was determined by laser nephelometry (BN II Analyzer) and CardioPhase high-sensitivity CR...

journal_title：Bosnian journal of basic medical sciences

authors： Zaciragić A,Huskić J,Hadzović-Dzuvo A,Valjevac A,Avdagić N,Mulabegović N

更新日期：2007-11-01 00:00:00

abstract：:The aim of this trial was to examine the efficacy and safety of antihypertensive fixed combination lisinopril plus hydrochlorothiazide (Lopril H, Bosnalijek dd) in the treatment of essential arterial hypertension. In our trial we included 297 patients, aged 54.65+/-9.6 years, with treated or untreated hypertension and...

journal_title：Bosnian journal of basic medical sciences

authors： Gerc V,Begović B,Vehabović M,Voronkov LG,Vataman E,Musić L,Buksa M,Kusljugić Z,Ilyash MG,Ena LM,Tchelujko VI,Dyaduk AI,Bagrij AE,Andrievskaja SA,Vehabović A,Knezević B,Hima F

更新日期：2007-11-01 00:00:00